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TMS Therapy Safety

Is TMS therapy safe?

TMS is considered an extremely safe method to manage depression without the potential side effects of medications. It uses significantly less magnetic energy but employs the same type and strength of magnetic fields used in MRIs, which have been safely used for tens of millions of people worldwide. Research has shown no negative brain effects, such as concentration difficulties or memory loss, from the treatment. There is a small risk of a seizure occurring during treatment, however this risk is no greater than has been observed with oral antidepressant medications.

Clinical trials have demonstrated the safety of TMS Therapy in treating patients who have had an inadequate response to prior antidepressant medications.

Treatment with TMS Therapy caused very few side effects and was generally well tolerated by patients. The most common side effect reported during clinical trials was scalp discomfort—generally mild to moderate and occurring less frequently after the first week of treatment.

Fewer than 5% of patients discontinued treatment with TMS Therapy due to adverse events.

Over 10,000 active treatments were performed across all clinical trials demonstrating its safety1

  • No systemic side effects
    • No weight gain
    • No sexual dysfunction
    • No sedation
    • No nausea
    • No dry mouth
  • No adverse effects on concentration or memory
  • No drug interactions
  • TMS Therapy should not be used in patients with implanted metallic devices or non-removable metallic objects in or around the head. This does not include metallic fillings in teeth.
  • TMS Therapy should not be used in patients with implants controlled by physiological signals. This includes pacemakers, implantable cardioverter defibrillators (ICDs), and vagus nerve stimulators (VNS).

Learn about a typical TMS Therapy treatment session.

References:

  1. Janicak, P, et al. Transcranial Magnetic Stimulation (TMS) in the Treatment of Major Depression: A Comprehensive Summary of Safety Experience from Acute Exposure, Extended Exposure and During Reintroduction Treatment. Journal of Clinical Psychiatry, February 2008.

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